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Functional genomics implicates natural killer cells as potential key drivers in the pathogenesis of ankylosing spondylitis.

Marcos ChiñasDaniela Fernandez-SalinasVitor R C AguiarVictor E Nieto-CaballeroMicah LeftonPeter A NigrovicJoerg ErmannMaria Gutierrez-Arcelus
Published in: medRxiv : the preprint server for health sciences (2023)
Our results point to NK cells as potential key drivers in the development of AS and highlight four putative target genes for functional follow-up in NK cells.
Keyphrases
  • nk cells
  • ankylosing spondylitis
  • natural killer cells
  • rheumatoid arthritis
  • disease activity
  • human health
  • systemic lupus erythematosus
  • gene expression
  • climate change