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LCP-Tacrolimus Extended-Release (Envarsus XR) Use in Adolescent and Young Adult Solid Organ Transplant Recipients.

Esther K BaeMary Moss ChandranMelanie D EverittEric BenzMargret E Bock
Published in: Clinical transplantation (2024)
Successful conversion from IR-Tac to LCP-Tac was demonstrated in AYA heart, kidney, and liver transplant recipients. These AYA SOT recipients experienced reduced pill burden and improved tacrolimus trough concentration variability. However, the impact on medication adherence warrants further investigation. Future research should explore the targeted use of LCP-Tac to enhance IS tolerability and medication adherence in young SOT populations.
Keyphrases
  • young adults
  • childhood cancer
  • heart failure
  • mental health
  • open label
  • cancer therapy
  • middle aged
  • double blind
  • study protocol
  • placebo controlled