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Comparison of logistic-regression based methods for simple mediation analysis with a dichotomous outcome variable.

Judith J M RijnhartJos W R TwiskIris EekhoutMartijn W Heymans
Published in: BMC medical research methodology (2019)
We advise the use of either the potential outcomes framework estimates or the ab estimate of the indirect effect and the ab/(ab + c') estimate of the proportion mediated based on multiple regression and SEM when mediation analysis is based on logistic regression. Standardization of the coefficients prior to estimating the indirect effect and the proportion mediated may not increase the performance of these estimates.
Keyphrases
  • type diabetes
  • adipose tissue
  • depressive symptoms
  • risk assessment
  • insulin resistance
  • weight loss