Elucidating the genetic landscape of oral leukoplakia to predict malignant transformation.

Leon J Wils Jos B Poell Arjen Brink Ilkay Evren Elisabeth R Brouns Jan G A M de Visscher Elisabeth Bloemena Ruud H Brakenhoff

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)

We provide an extensive description of genetic alterations in oral leukoplakia and its relation to malignant transformation. Based on our data we provide a model for the prediction of malignant transformation of oral leukoplakia using dysplasia and genetic markers.

Keyphrases

genome wide
copy number
electronic health record
big data
machine learning
deep learning