Early innate role for CD8αα+ cells in tuberculosis.

Published in: The Journal of experimental medicine (2023)

Cell types that mediate early control of Mycobacterium tuberculosis (Mtb) infection are not well understood. Winchell and Nyquist et al. (https://doi.org/10.1084/jem.20230707) show that CD8αα+ lymphocytes have a major role in the innate suppression of Mtb growth in the lungs of macaques.

Keyphrases

mycobacterium tuberculosis
pulmonary tuberculosis
immune response
induced apoptosis
cell cycle arrest
emergency department
signaling pathway
cell proliferation
cell death
adverse drug
human immunodeficiency virus