Targeting the Ezrin Adaptor Protein Sensitizes Metastatic Breast Cancer Cells to Chemotherapy and Reduces Neoadjuvant Therapy-induced Metastasis.
Victoria HoskinAbdi GhaffariBrian J LaightSandip SenGuptaYolanda MadarnasChristopher J B NicolBruce E ElliottSonal VarmaPeter A GreerPublished in: Cancer research communications (2022)
This work provides preclinical evidence for combining anti-ezrin treatment with chemotherapy as a novel strategy for effectively targeting metastasis, particularly in a neoadjuvant treatment setting.