[COVID-19 and features of cardiovascular involvement].
E V TsyganovaN V GlukhoedovaA S ZhilenkovaT I FedoseevaE N YushchukN S SmetnevaPublished in: Terapevticheskii arkhiv (2021)
The article provides an overview of current information on the pathogenesis of COVID-19 and organ-specific lesions developing in this disease. The data on inflammation and its biochemical markers, on the features of coagulopathy, endothelial damage and microthrombosis are presented in detail. Particular attention is paid to the role of receptors for angiotensin converting enzyme type 2 and transmembrane serine protease type 2 in the development of organ-specific lesions in COVID-19. The pathogenesis of damage to the cardiovascular system is considered in detail with the presentation of data from foreign literature on changes in the myocardium and the author's results of transthoracic echocardiographic examination in patients who have undergone COVID-19.
Keyphrases
- coronavirus disease
- sars cov
- angiotensin converting enzyme
- oxidative stress
- end stage renal disease
- ejection fraction
- angiotensin ii
- electronic health record
- chronic kidney disease
- systematic review
- big data
- newly diagnosed
- peritoneal dialysis
- heart failure
- mitral valve
- machine learning
- artificial intelligence
- deep learning