Diagnostic clues indicating tall cell variants of papillary thyroid carcinoma in fine needle aspiration.

Aki TanakaMitsuyoshi HirokawaMiyoko HiguchiAyana SuzukiNaoki YamaoToshitetsu HayashiSeiji KumaAkira Miyauchi

Published in: Diagnostic cytopathology (2018)

It is the most important to identify the presence of the tall columnar carcinoma cells on the cytological preparations, in order to distinguish TCV-PTC from C-PTC. We propose five cytological findings indicating TCV-PTC, (1) palisaded pattern, (2) tall columnar cells with the heights of at least three times their widths, (3) tombstone appearance, (4) spindle-like carcinoma cells, and (5) cytoplasmic elongation.

Keyphrases

fine needle aspiration
ultrasound guided
induced apoptosis
cell cycle arrest
single cell
lymph node
lymph node metastasis
cell therapy
copy number
endoplasmic reticulum stress
signaling pathway
oxidative stress
stem cells
mesenchymal stem cells
pi k akt