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Hepatoprotective Activity of Leptadenia hastata (Asclepiadaceae) on Acetaminophen-Induced Toxicity in Mice: In Vivo Study and Characterization of Bioactive Compounds through Molecular Docking Approaches.

Borris Rosnay Tietcheu GalaniBrice Ayissi OwonaDieudonné P D ChuisseuEsaïe MachewereClaude B N NgantchoukoPaul Fewou Moundipa
Published in: BioMed research international (2020)
Based on these results, L. hastata could be considered a source of promising hepatoprotective compounds with antioxidant and anti-inflammatory properties.
Keyphrases
  • molecular docking
  • anti inflammatory
  • oxidative stress
  • molecular dynamics simulations
  • diabetic rats
  • high glucose
  • drug induced
  • liver injury
  • high fat diet induced
  • adipose tissue
  • metabolic syndrome
  • wild type