Alterations in the gut microbiome and metabolism with coronary artery disease severity.
Honghong LiuXi ChenXiaomin HuHaitao NiuRan TianHui WangHaiyu PangLingjuan JiangBintao QiuXiuting ChenYang ZhangYiyangzi MaSi TangHanyu LiSiqin FengShu-Yang ZhangChenhong ZhangPublished in: Microbiome (2019)
Overall, the composition and functions of the gut microbial community differed from healthy controls to diverse coronary artery disease subtypes. Our study identified the relationships between the features of the gut microbiota and circulating metabolites, providing a new direction for future studies aiming to understand the host-gut microbiota interplay in atherosclerotic pathogenesis.
Keyphrases
- microbial community
- coronary artery disease
- percutaneous coronary intervention
- antibiotic resistance genes
- cardiovascular events
- coronary artery bypass grafting
- ms ms
- current status
- cardiovascular disease
- type diabetes
- wastewater treatment
- aortic stenosis
- atrial fibrillation
- left ventricular
- transcatheter aortic valve replacement