Detection of Alteration in Carotid Artery Volumetry Using Standard-of-care Computed Tomography Surveillance Scans Following Unilateral Radiation Therapy for Early-stage Tonsillar Squamous Cell Carcinoma Survivors: A Cross-Sectional Internally-Matched Carotid Isodose Analysis.
Efstratios KoutroumpakisMohamed A NaserAbdallah Sherif Radwan MohamedSalman A ErajAndrea JarreJay C ShiaoMona KamalSubha PerniJack P PhanWilliam H MorrisonSteven J FrankG Brandon GunnAdam S GardenAnita DeswalJun-Ichi AbeDavid I RosenthalElie MouhayarClifton David FullerPublished in: medRxiv : the preprint server for health sciences (2024)
Our data show that standard-of-care oncologic surveillance CT scans can effectively detect reductions in carotid volume following RT for oropharyngeal cancer. Changes were equivalent between studied dose ranges, denoting no further dose-response effect beyond 50 Gy. The clinical utility of carotid volume changes for risk stratification and CVA prediction warrants further evaluation.
Keyphrases
- computed tomography
- dual energy
- early stage
- squamous cell carcinoma
- positron emission tomography
- contrast enhanced
- healthcare
- palliative care
- public health
- image quality
- quality improvement
- magnetic resonance imaging
- papillary thyroid
- pain management
- affordable care act
- young adults
- electronic health record
- rectal cancer
- prostate cancer
- radiation therapy
- squamous cell
- robot assisted
- health insurance
- chronic pain
- machine learning
- neoadjuvant chemotherapy
- data analysis
- sensitive detection