Specnuezhenide ameliorates hepatic fibrosis via regulating SIRT6-Mediated inflammatory signaling cascades.
Bo-Feng QinJin-Jin ZhangQi-Yuan FengXin GuoHai-Ming SunJian Song
Published in: Journal of ethnopharmacology (2024)
Therefore, SP decreased inflammatory response via SIRT6-P2X7R/NLRP3 pathway and suppressed fibrillogenesis. These findings supported SP as the novel candidate to treat hepatic fibrosis.