MTFR2-dependent mitochondrial fission promotes HCC progression.

La ZhangXiuzhen ZhangHaichuan LiuChanghong YangJiyao YuWei ZhaoJiao GuoBaoyong ZhouNing Jiang

Published in: Journal of translational medicine (2024)

In conclusion, we developed a novel MTFR2-related prognostic signature comprising ten mitochondrial dynamics genes. These genes play crucial roles in mitochondrial fission and have the potential to serve as important predictors and therapeutic targets for HCC.

Keyphrases

oxidative stress
genome wide
bioinformatics analysis
genome wide identification
dna methylation
risk assessment
transcription factor
genome wide analysis