Moderately hypofractionated versus conventionally fractionated radiation therapy with temozolomide for young and fit patients with glioblastoma: an institutional experience and meta-analysis of literature.
Phoebe ChidleyMihir ShankerClaire PhillipsNeda HaghighiMark B PinkhamJames R WhittleJoseph SiaPublished in: Journal of neuro-oncology (2022)
HF-RT may offer equivalent outcomes and reduce treatment burden compared to CF-RT in young, fit GBM patients.
Keyphrases
- radiation therapy
- newly diagnosed
- end stage renal disease
- ejection fraction
- systematic review
- chronic kidney disease
- middle aged
- prognostic factors
- peritoneal dialysis
- type diabetes
- small cell lung cancer
- squamous cell carcinoma
- metabolic syndrome
- radiation induced
- brain metastases
- patient reported outcomes
- locally advanced
- acute heart failure
- weight loss
- combination therapy
- glycemic control
- replacement therapy