Plant-based dietary patterns, genetic predisposition and risk of colorectal cancer: a prospective study from the UK Biobank.
Fubin LiuYanling LvYu PengYating QiaoPeng WangChangyu SiXixuan WangJianxiao GongHuijun ZhouMing ZhangLiangKai ChenFangfang SongPublished in: Journal of translational medicine (2023)
Our results suggested that better adherence to overall and healthful plant-based diets was associated with a lower risk of CRC, whereas an unhealthful plant-based diet was associated with a higher CRC risk. Consumption of a higher-quality plant-based diet combined with decreased genetic risk conferred less susceptibility to CRC. Our findings highlighted the importance of food quality when adhering to a plant-based dietary pattern for CRC prevention in the general population.