Influence of phendimetrazine maintenance on the reinforcing, subjective, performance, and physiological effects of intranasal cocaine.

William W StoopsJustin C StricklandJoseph L AlcornLon R HaysAbner O RayapatiJoshua A LileCraig R Rush

Published in: Psychopharmacology (2019)

These results indicate that although phendimetrazine can safely be combined with cocaine, it does not attenuate the abuse-related effects of cocaine. It is unlikely, then, that phendimetrazine will be an effective standalone treatment for cocaine use disorder.

Keyphrases

prefrontal cortex
sleep quality
combination therapy
depressive symptoms