Emergence as an outbreak of the HIV-1 CRF19_cpx variant in treatment-naïve patients in southern Spain.

Carmen Maria Gonzalez-DomenechIsabel VicianaLuis DelayeMaría Luisa MayorgaRosario PalaciosJavier de la TorreFrancisco JarillaManuel CastañoAlfonso Del ArcoEncarnación ClavijoJesús Santos

Published in: PloS one (2018)

We report the largest HIV-1 CRF19_cpx cohort of treatment-naïve patients outside Cuba, almost all emerging as an outbreak in the South of Spain. Half the cases had the G190A resistance mutation. Unlike previous studies, the variant from Malaga seems less pathogenic, with few AIDS events and an excellent response to ART.

Keyphrases

antiretroviral therapy
end stage renal disease
newly diagnosed
ejection fraction
human immunodeficiency virus
hepatitis c virus
hiv positive
patient reported outcomes
patient reported