Biomarkers and prediction of anthracyclic cardiotoxicity in breast cancer.
Eduardo Nani SilvaMario Luiz RibeiroLilian Campos CaldeiraAntonio José Lagoeiro JorgeMaria Luiza Garcia RosaEvandro Tinoco MesquitaHumberto Villacorta JuniorWolney de Andrade MartinsPublished in: Revista da Associacao Medica Brasileira (1992) (2024)
Troponin I, type B natriuretic peptide, myoglobin, and creatine phosphokinase fraction MB are elevated during chemotherapy with doxorubicin, but they were not able to predict cardiotoxicity according to established clinical and echocardiographic criteria. The incidence of subclinical cardiotoxicity resulting from the administration of doxorubicin was 12.5%.