Single Nucleotide Polymorphisms in APE1, hOGG1, RAD51 Genes and their Association with Radiotherapy Induced Toxicity among Head and Neck Cancer Patients.

Anand K GudurShivani R KaleRashmi A GudurSuresh J BhosaleAshwini L MoreKailas D Datkhile

Published in: Asian Pacific journal of cancer prevention : APJCP (2024)

Interpretation of our results revealed significant association of rs1801321 SNP of Rad51 with development of adverse toxicity reactions in normal tissue of head and neck cancer patients treated with radiotherapy.

Keyphrases

early stage
dna damage
dna repair
genome wide
locally advanced
oxidative stress
radiation induced
radiation therapy
diabetic rats
high glucose
single cell
squamous cell carcinoma
rectal cancer
drug induced
high density
genome wide identification