Complications and Outcomes of Diaphragm Surgeries in Epithelial Ovarian Malignancies.
Amrita DattaAjit SebastianRachel George ChandyVinotha ThomasDhanya Susan ThomasReka KaruppusamiAnitha ThomasAbraham PeedicayilPublished in: Indian journal of surgical oncology (2021)
To achieve optimal debulking, cytoreductive surgery often involves diaphragm stripping. We describe our complications and survival outcomes after diaphragm surgery in epithelial ovarian cancer. A retrospective analysis on patients with advanced stage epithelial ovarian cancer between January 2012 and September 2019. The details of the diaphragmatic resections and stripping and their complications were looked into. During the study period, 616 patients with epithelial ovarian cancers were operated of which, 81 (13.2%) had diaphragm surgery. The majority underwent diaphragm stripping (60%) while 33% had resection and 7% cases had diaphragmatic nodule excision. Optimal debulking was achieved in 89% of cases. The complexity of surgery was intermediate in 64% of patients and complex in 33% as per Aletti's scoring. Mean operating time was 300 min (SD113). Moderate to severe pleural effusion was seen in 26 (32. %) patients necessitating pleural tapping in 16% and single lumen pleurex catheter insertion in 11%. Median recurrence-free and overall survival were 22 (95% CI 16.9-27) and 32 months (95% CI 25.5-38) respectively. Diaphragm stripping and resection is an important step in achieving optimal debulking of advanced and recurrent ovarian cancer. Diaphragmatic disease clearance is a necessary skill to be acquired by the gynaecologic oncology surgeons. Choosing the patients correctly and anticipation of complications can reduce morbidity and mortality.
Keyphrases
- end stage renal disease
- minimally invasive
- ejection fraction
- newly diagnosed
- mechanical ventilation
- coronary artery bypass
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- neoadjuvant chemotherapy
- risk factors
- type diabetes
- squamous cell carcinoma
- metabolic syndrome
- early onset
- acute respiratory distress syndrome
- surgical site infection
- patient reported
- insulin resistance
- percutaneous coronary intervention
- liver metastases