Synthesis of benzothiazole compounds based on 2D graphene oxide membrane nanoreactors.

The nanoconfinement effect plays an important role in chemical reactions. Inspired by enzymes, this work presents a new way to conduct the rapid flow synthesis of benzothiazoles in the two-dimensional (2D) nanoconfined space created by a graphene oxide membrane. The conversion reaches 96.7% in a short reaction time of less than 23 s at 22 °C.