Increased Resting-State Functional Connectivity as a Compensatory Mechanism for Reduced Brain Volume in Prediabetes and Type 2 Diabetes.
Xin-Miao ZhangChang LiuWanlin ZhuYue-Song PanJiyang JiangXueli CaiZhe ZhangZixiao LiYijun ZhouXia MengJian ChengYi-Long WangHao LiYong JiangHuaguang ZhengSuying WangHaijun NiuWei WenPerminder S SachdevTiemin WeiTao LiuYong-Jun WangPublished in: Diabetes care (2023)
Cognition was associated with greater brain volume and lower functional connectivity in T2DM. Increased functional connectivity may indicate a compensatory mechanism for reduced brain volume that begins in the prediabetic phase.