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Increased Resting-State Functional Connectivity as a Compensatory Mechanism for Reduced Brain Volume in Prediabetes and Type 2 Diabetes.

Xin-Miao ZhangChang LiuWanlin ZhuYue-Song PanJiyang JiangXueli CaiZhe ZhangZixiao LiYijun ZhouXia MengJian ChengYi-Long WangHao LiYong JiangHuaguang ZhengSuying WangHaijun NiuWei WenPerminder S SachdevTiemin WeiTao LiuYong-Jun Wang
Published in: Diabetes care (2023)
Cognition was associated with greater brain volume and lower functional connectivity in T2DM. Increased functional connectivity may indicate a compensatory mechanism for reduced brain volume that begins in the prediabetic phase.
Keyphrases
  • resting state
  • functional connectivity
  • type diabetes
  • cardiovascular disease
  • white matter
  • mild cognitive impairment
  • adipose tissue
  • skeletal muscle
  • blood brain barrier