G protein-coupled estrogen receptor 1 (GPER-1) and agonist G-1 inhibit growth of ovarian cancer cells by activation of anti-tumoral transcriptome responses: impact of GPER-1 mRNA on survival.
Susanne Schüler-ToprakMaciej SkrzypczakTanja IgnatovAtanas IgnatovOlaf OrtmannOliver TreeckPublished in: Journal of cancer research and clinical oncology (2020)
The results of this study clearly support the hypothesis that GPER-1 acts as a tumor suppressor in ovarian cancer.