Divergent Hypoglycemic Effects of Hepatic-Directed Prandial Insulin: A 6-Month Phase 2b Study in Type 1 Diabetes.

David C Klonoff Bruce W BodeNathan CohenMarc PennW Blair GehoDouglas B Muchmore

Published in: Diabetes care (2019)

Hepatic biodistribution of HDV-L appears to potentiate insulin effect in T1D, with divergent clinical outcomes in hypoglycemia dependent on baseline A1C.

Keyphrases

type diabetes
glycemic control
insulin resistance
cardiovascular disease
metabolic syndrome
computed tomography
positron emission tomography