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Availability of PEth testing is associated with reduced eligibility for liver transplant among patients with alcohol-related liver disease.

Ranya SelimYueren ZhouLoralee B RuppSheri TrudeauSandra NaffoujOmar ShamaaAbdelwahab AhmedSyed-Mohammed JafriStuart C GordonAntu SegalHumberto C Gonzalez
Published in: Clinical transplantation (2022)
Three hundred and seventy-five patients with alcohol-related indications for transplant (157 in 2017; 210 in 2019) were included. The final IPW-adjusted model for the composite outcome of terminations/delisting due to alcohol use retained two significant variables (P < .05): PEth era and BMI category. Patients evaluated during the PEth era were almost three times more likely to experience an alcohol-related termination/delisting than those in the pre-PEth era (sHR = 2.86; 95%CI 1.67-4.97) CONCLUSION: We found that availability of PEth testing at our institution was associated with a higher rate of exclusion of patients from eligibility for liver transplant. Use of PEth testing has significant potential to inform decisions regarding transplant candidacy for patients with alcohol-related liver disease.
Keyphrases
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • chronic kidney disease
  • prognostic factors
  • peritoneal dialysis
  • alcohol consumption
  • body mass index
  • patient reported outcomes
  • risk assessment