Availability of PEth testing is associated with reduced eligibility for liver transplant among patients with alcohol-related liver disease.
Ranya SelimYueren ZhouLoralee B RuppSheri TrudeauSandra NaffoujOmar ShamaaAbdelwahab AhmedSyed-Mohammed JafriStuart C GordonAntu SegalHumberto C GonzalezPublished in: Clinical transplantation (2022)
Three hundred and seventy-five patients with alcohol-related indications for transplant (157 in 2017; 210 in 2019) were included. The final IPW-adjusted model for the composite outcome of terminations/delisting due to alcohol use retained two significant variables (P < .05): PEth era and BMI category. Patients evaluated during the PEth era were almost three times more likely to experience an alcohol-related termination/delisting than those in the pre-PEth era (sHR = 2.86; 95%CI 1.67-4.97) CONCLUSION: We found that availability of PEth testing at our institution was associated with a higher rate of exclusion of patients from eligibility for liver transplant. Use of PEth testing has significant potential to inform decisions regarding transplant candidacy for patients with alcohol-related liver disease.