Evaluation of 1,10-phenanthroline-based hydroxamate derivative as dual histone deacetylases/ribonucleotide reductase inhibitor with antitumor activities.

Manasa Gangadhar ShettyPadmini PaiBipasa DeyKapaettu SatyamoorthySuranjan ShilUsha Yogendra NayakAshwini TKampa Sundara Babitha

Published in: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences (2024)

The present study emphasizes the prospect of designing a potential 1,10-phenanthroline hydroxamic acid derivative as a novel dual HDAC and RR-inhibiting anti-cancer molecule.

Keyphrases

signaling pathway
water soluble
gene expression
current status
climate change