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Gene expression profiling of inflammatory cytokines in esophageal biopsies of different phenotypes of gastroesophageal reflux disease: a cross-sectional study.

Mónica R Zavala-SolaresGabriela Fonseca-CamarilloMiguel ValdovinosJulio GranadosGuido Grajales-FigueroaLuis Zamora-NavaNancy Aguilar-OlivosLuis R Valdovinos-GarcíaJesus K Yamamoto-Furusho
Published in: BMC gastroenterology (2021)
This study demonstrates the differential expression of mediators of inflammation in the esophageal mucosa of patients with different GERD endoscopic phenotypes. IL-1B and TNF-α could be useful to differentially diagnose AAE and NAE in the non-erosive phenotype using endoscopic biopsies.
Keyphrases
  • ultrasound guided
  • gastroesophageal reflux disease
  • gene expression
  • oxidative stress
  • rheumatoid arthritis
  • dna methylation
  • physical activity
  • endoscopic submucosal dissection
  • genome wide analysis