Gene expression profiling of inflammatory cytokines in esophageal biopsies of different phenotypes of gastroesophageal reflux disease: a cross-sectional study.
Mónica R Zavala-SolaresGabriela Fonseca-CamarilloMiguel ValdovinosJulio GranadosGuido Grajales-FigueroaLuis Zamora-NavaNancy Aguilar-OlivosLuis R Valdovinos-GarcíaJesus K Yamamoto-FurushoPublished in: BMC gastroenterology (2021)
This study demonstrates the differential expression of mediators of inflammation in the esophageal mucosa of patients with different GERD endoscopic phenotypes. IL-1B and TNF-α could be useful to differentially diagnose AAE and NAE in the non-erosive phenotype using endoscopic biopsies.