Extracellular RNA Induces Neutrophil Recruitment Via Toll-Like Receptor 3 During Venous Thrombosis After Vascular Injury.
Maria Y NajemRyan N RysSandrine LauranceFrancois Rene BertinVirginie Gourdou-LatyszenokLénaïck GourhantLauriane Le GallRozenn Le CorreFrancis CouturaudMark D BlosteinCatherine A LemariéPublished in: Journal of the American Heart Association (2024)
We show that eRNA and TLR3 activation enhance venous thromboembolism through neutrophil recruitment possibly through secretion of CXCL5, a potent neutrophil chemoattractant.