Lifestyle factors and genetic variants on two biological age measures: evidence from 94,443 Taiwan Biobank participants.

Published in: The journals of gerontology. Series A, Biological sciences and medical sciences (2021)

A PhenoAgeAccel-associated SNP (rs1260326 in GCKR) and two BioAgeAccel-associated SNPs (rs7412 in APOE; rs16998073 near FGF5) were consistent with the finding from the UK Biobank. The lifestyle analysis shows that prevention from obesity, cigarette smoking, and alcohol consumption is associated with a slower rate of biological aging.

Keyphrases

alcohol consumption
metabolic syndrome
weight loss
genome wide
physical activity
cardiovascular disease
insulin resistance
type diabetes
high fat diet
gene expression
body mass index
genetic diversity
high density