Effects of choline supplementation in mothers with hypothyroidism on the brain-derived neurotrophic factor gene expression changes in pre-pubertal offspring rats.

Siamak SheikhiLeila DerafshpourRazieh AghazadehHojat SayyadiEhsan SabooryMorteza Bagheri

Published in: Molecular biology reports (2022)

It can be concluded that maternal choline supplementation on the first day of gestation until PND 21 improves brain development and cognitive function in pre-pubertal offspring rats regarding control/hypothyroidism groups.

Keyphrases

gene expression
high fat diet
dna methylation
replacement therapy
preterm infants
resting state
birth weight
adipose tissue
insulin resistance
functional connectivity
pregnancy outcomes