Flavopiridol's effects on metastasis in KRAS mutant lung adenocarcinoma cells.

Irem Dogan TuracliFunda Demirtas KorkmazTuba CandarAbdullah Ekmekci

Published in: Journal of cellular biochemistry (2018)

Although there are many mechanisms that still need to be elucidated, flavopiridol can be used as a metastasis inhibitor and an apoptosis inducer in KRAS mutant NSCLC.

Keyphrases

wild type
cell cycle arrest
induced apoptosis
cell death
endoplasmic reticulum stress
small cell lung cancer
oxidative stress
pi k akt
cell proliferation