Disruption of COMMD1 accelerates diabetic atherosclerosis by promoting glycolysis.
Lili ZhangLihua LiYalan LiHan JiangZhen SunGuangyao ZangYongjiang QianChen ShaoZhongqun WangPublished in: Diabetes & vascular disease research (2023)
Taken together, we provided evidence that the lack of COMMD1 accelerates diabetic atherosclerosis via mediating the metabolic reprogramming of macrophages. Our study provides evidence of a protective role for COMMD1 and establishes COMMD1 as a potential therapeutic strategy in patients with diabetic atherosclerosis.