Electric Field Strength From Prefrontal Transcranial Direct Current Stimulation Determines Degree of Working Memory Response: A Potential Application of Reverse-Calculation Modeling?

Kevin A CaulfieldAprinda IndahlastariNicole R NissimJames W LopezHolly H FleischmannAdam J WoodsMark S George

Published in: Neuromodulation : journal of the International Neuromodulation Society (2020)

Higher electric fields at the left DLPFC from uniform 2 mA doses appear to drive working memory improvements from tDCS. Individualized doses from reverse-calculation modeling significantly reduce electric field variance at the cortex. Taken together, using reverse-calculation modeling to produce the same, high electric fields at the cortex across participants may produce more effective future tDCS treatments for working memory.

Keyphrases

working memory
transcranial direct current stimulation
attention deficit hyperactivity disorder
functional connectivity
monte carlo
risk assessment
current status
human health
climate change
high frequency