Genetic Implication of Prenatal GABAergic and Cholinergic Neuron Development in Susceptibility to Schizophrenia.

Darren CameronNgoc-Nga VinhParinda PrapaiwongsElizabeth A PerryJames T R WaltersMeng LiMichael C O'DonovanNicholas J Bray

Published in: Schizophrenia bulletin (2024)

Our study implicates prenatal development of specific populations of GABAergic and cholinergic neurons in later susceptibility to schizophrenia, and provides a map of predicted regulatory genomic elements operating in cells of the GE.

Keyphrases

bipolar disorder
pregnant women
copy number
spinal cord
genome wide
oxidative stress
dna methylation
genetic diversity
high density
endoplasmic reticulum stress