Polydatin Prevents Calcium Pyrophosphate Crystal-Induced Arthritis in Mice.

Francesca Oliviero Paola GalozziAnna ScanuFrancesca GaluppiniVanni LazzarinSilvia BroccoGiampietro RavagnanPaolo SfrisoRoberta RamondaPaolo SpinellaLeonardo PunziGianmaria PennelliRoberto Luisetto

Published in: Nutrients (2021)

PD can effectively prevent acute inflammatory response to crystals in the mouse model of CPP crystal-induced arthritis. These results suggest that this bioactive compound might be used in the prevention of crystal-induced acute attacks in humans.

Keyphrases

mouse model
high glucose
drug induced
rheumatoid arthritis
diabetic rats
oxidative stress
type diabetes
endothelial cells
adipose tissue
intensive care unit
respiratory failure
room temperature
skeletal muscle
wild type