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Myosin in autoinhibited off state(s), stabilized by mavacamten, can be recruited via inotropic effectors.

Weikang MaCarlos L Del RioLin QiMomcilo ProdanovicSrboljub M MijailovichChristopher ZambataroHenry GongRafael ShimkunasSampath K GollapudiSuman NagThomas C Irving
Published in: bioRxiv : the preprint server for biology (2023)
) with exercise in HCM patients receiving mavacamten.
Keyphrases
  • high intensity
  • hypertrophic cardiomyopathy
  • binding protein
  • physical activity
  • type iii
  • resistance training
  • heart failure
  • left ventricular