Multi-institutional Analysis of the Clinical and Genomic Characteristics of Black Patients with Metastatic Hormone-Sensitive Prostate Cancer.

Meredith N FreemanAlbert JangJason ZhuFarhad SanatiLakshminarayanan NandagopalDeepak RavindranathanArpita DesaiAudrey PhoneRoberto NussenzveigEllen JaegerSydney A CaputoVadim S KoshkinUmang SwamiArnab BasuMehmet A BilenNeeraj AgarwalOliver SartorEarle F BurgessPedro C Barata

Published in: The oncologist (2022)

In our cohort, Black men with mHSPC presented with a high proportion of de novo metastases and high-volume disease. Treatment outcomes were very favorable with ADT-based regimens. The genomic landscape suggests different molecular profile relative to White patients with potential therapeutic implications.

Keyphrases

prostate cancer
copy number
radical prostatectomy
middle aged
single cell
single molecule