Measures of obesity are associated with MRI markers of brain aging: The Northern Manhattan Study.

Michelle R CauncaHannah GardenerMarialaura SimonettoYing Kuen CheungNoam AlperinMitsuhiro YoshitaCharles DeCarliMitchell S V ElkindRalph L SaccoClinton B WrightTatjana Rundek

Published in: Neurology (2019)

Adiposity in early-old age is related to reduced global gray matter later in life in this diverse sample. Future studies are warranted to elucidate causal relationships and explore region-specific associations.

Keyphrases

insulin resistance
weight gain
metabolic syndrome
magnetic resonance imaging
type diabetes
weight loss
white matter
contrast enhanced
current status
resting state
multiple sclerosis
body mass index
skeletal muscle
computed tomography
diffusion weighted imaging
case control
blood brain barrier