Proteomic analysis of bone marrow-derived mesenchymal stem cell extracellular vesicles from healthy donors: implications for proliferation, angiogenesis, Wnt signaling, and the basement membrane.
Jeffrey D McBrideLuis Rodriguez-MenocalWellington GuzmanAisha KhanCiara MyerXiaochen LiuSanjoy K BhattacharyaEvangelos V BadiavasPublished in: Stem cell research & therapy (2021)
Healthy donors of BM-MSC EVs contain important similarities and differences among protein cargo that may play important roles in their pro-regenerative functions. Further studies are needed to correlate proteomic signatures to functional outcomes in cutaneous repair.