Cardiac structural and functional abnormalities in primary hyperparathyroidism.
S PurraA A LoneMoomin Hussain BhatRaiz Ahmad MisgarArshad Iqbal WaniMir Iftikhar BashirShariq Rashid MasoodiW PurraPublished in: Journal of endocrinological investigation (2021)
Symptomatic patients with PHPT have substantial cardiac structural and functional abnormalities. These abnormalities include elevated LVMI, diastolic dysfunction, and aortic valve, mitral annular, septal and myocardial calcifications. We strongly suggest and conclude that the evaluation of PHPT patients should not only include traditional end organs like bones and kidneys but also the cardiovascular system in the form of echocardiography to detect subclinical cardiac dysfunction so that the cardiovascular health of such patients can be optimized.
Keyphrases
- left ventricular
- aortic valve
- ejection fraction
- end stage renal disease
- aortic stenosis
- newly diagnosed
- chronic kidney disease
- prognostic factors
- oxidative stress
- blood pressure
- computed tomography
- mitral valve
- transcatheter aortic valve replacement
- aortic valve replacement
- left atrial
- coronary artery disease
- atrial fibrillation