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Successful Matched Related Bone Marrow Transplantation in a Patient with Autosomal Dominant Interferon Gamma Receptor 1 Deficiency.

Christa S ZerbeDimana DimitrovaJuan J Gea-BanaclocheSamantha KreuzburgSteven M HollandJennifer A Kanakry
Published in: Journal of clinical immunology (2020)
A successful curative HCT despite persistent, disseminated, nontuberculous mycobacterial infection in a patient with AD-IFNγR1 suggests that this approach, while difficult, may be useful in other patients with otherwise refractory disease.
Keyphrases
  • bone marrow
  • case report
  • dendritic cells
  • mesenchymal stem cells
  • mycobacterium tuberculosis
  • immune response
  • rectal cancer
  • cell proliferation
  • replacement therapy
  • signaling pathway
  • binding protein
  • cell death