Response prediction of neoadjuvant chemoradiation therapy in locally advanced rectal cancer using CT-based fractal dimension analysis.
Toru TochigiSophia C KamranAnushri ParakhYoshifumi NodaBalaji GaneshanLawrence S BlaszkowskyDavid P RyanJill N AllenDavid L BergerJennifer Y WoTheodore S HongAvinash R KambadakonePublished in: European radiology (2021)
• Fractal dimension analysis on pretreatment CT was associated with response to neo-adjuvant chemoradiation in patients with locally advanced rectal cancer. • Fractal dimension is a promising biomarker for predicting pCR to nCRT and may potentially select patients for individualized therapy.
Keyphrases
- rectal cancer
- locally advanced
- neoadjuvant chemotherapy
- phase ii study
- squamous cell carcinoma
- radiation therapy
- end stage renal disease
- image quality
- ejection fraction
- chronic kidney disease
- magnetic resonance imaging
- contrast enhanced
- peritoneal dialysis
- prognostic factors
- stem cells
- clinical trial
- magnetic resonance
- cell therapy
- pet ct
- smoking cessation
- open label