Assessment of autonomic symptoms may assist with early identification of mild cognitive impairment with Lewy bodies.
Calum Alexander HamiltonJames FrithPaul C DonaghySally A H BarkerRory DurcanSarah LawleyNicola BarnettMichael FirbankGemma RobertsJohn-Paul TaylorLouise M AllanJohn O'BrienAlison J YarnallAlan J ThomasPublished in: International journal of geriatric psychiatry (2022)
Mild cognitive impairment with Lewy bodies had greater autonomic symptom severity than normal ageing and MCI-AD, but such autonomic symptoms are not a specific finding. The COMPASS-31 may therefore have value as a sensitive screening test for early-stage Lewy body disease.