Brain Structure Among Middle-aged and Older Adults With Long-standing Type 1 Diabetes in the DCCT/EDIC Study.

Alan M JacobsonBarbara H BraffettGuray ErusChristopher M RyanGeert Jan BiesselsJosé A LuchsingerIonut Bebu Rose A Gubitosi-KlugLisa DesiderioGayle M LorenziVictoria R TrapaniJohn M LachinR Nick BryanMohamad HabesIlya M Nasrallahnull null

Published in: Diabetes care (2022)

Middle-aged and older adults with T1DM showed brain volume loss and increased vascular injury in comparison with control subjects without diabetes, equivalent to 4-9 years of brain aging.

Keyphrases

type diabetes
resting state
white matter
glycemic control
cardiovascular disease
physical activity
functional connectivity
cerebral ischemia
insulin resistance
metabolic syndrome
brain injury
subarachnoid hemorrhage
clinical evaluation