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Synthesis of Diaryl Ethers via Hypervalent Iodine-Mediated C-H Functionalization.

Chenghu HuQi JiaWenjing BaoGuangxing GuYa LiYanchuan Zhao
Published in: Organic letters (2024)
A hypervalent iodine-reagent-based C-H functionalization strategy was utilized to synthesize diaryl ethers. This method directly transforms various arenes into their corresponding diaryliodonium salts, followed by a C-O coupling reaction to produce structurally diverse diaryl ethers. The efficacy of this approach in the late-stage structural modifications of complex molecules was demonstrated.
Keyphrases
  • dual energy
  • ionic liquid
  • magnetic resonance imaging
  • electron transfer