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Thoracic mesenchymal malignant tumors and programed cell death ligand-1 status: Clinicopathologic and prognostic analysis of eight pulmonary sarcomatoid carcinomas and eight malignant mesotheliomas.

Kanji OtsuboHiroki SakaiHiroyuki KimuraTomoyuki MiyazawaHideki MarushimaKoji KojimaNaoki FuruyaMasamichi MineshitaMotohiro ChosokabeJunki KoikeHisashi Saji
Published in: Thoracic cancer (2021)
The present study showed that sarcomatoid carcinoma had a higher PD-L1 expression compared to non-small-cell lung cancer and that both PSC and MPM tended to exhibit PD-L1 positivity in the sarcomatoid compartment. Moreover, while immune checkpoint inhibitors may somewhat prolong the prognosis of both tumors, further studies with a larger cohort are necessary to confirm our results.
Keyphrases
  • cell death
  • pulmonary hypertension
  • stem cells
  • spinal cord
  • spinal cord injury