Schisandra chinensis bee pollen's chemical profiles and protective effect against H2O2-induced apoptosis in H9c2 cardiomyocytes.

Peiying ShiQianqian GengLifu ChenTianyu DuYan LinRongcai LaiFei MengZhenhong WuXiaoqing MiaoHong Yao

Published in: BMC complementary medicine and therapies (2020)

This study is the first to report that SCBPE could protect against oxidative stress injury and apoptosis in H2O2-injured H9c2 cells. Results indicated that the nucleosides and quinic acid nitrogen-containing derivatives could be the main substances that exert protective effects against H2O2-induced H9c2 cardiomyocyte injury.

Keyphrases

induced apoptosis
oxidative stress
endoplasmic reticulum stress
diabetic rats
high glucose
signaling pathway
dna damage
ischemia reperfusion injury
drug induced
angiotensin ii
drinking water
cell proliferation