Regular use of proton pump inhibitors and risk of type 2 diabetes: results from three prospective cohort studies.

Jinqiu YuanQiangsheng HeLong H Nguyen Martin C S Wong Martin Chi-Sang WongYuanyuan YuBin XiaYan TangYu-Long He Changhua Zhang

Published in: Gut (2020)

Regular use of PPIs was associated with a higher risk of type 2 diabetes and the risk increased with longer duration of use. Physicians should therefore exercise caution when prescribing PPIs, particularly for long-term use.

Keyphrases

type diabetes
primary care
emergency department
metabolic syndrome
glycemic control
skeletal muscle
adipose tissue
weight loss