Discovery of Ten Anti-HIV Hit Compounds and Preliminary Pharmacological Mechanisms Studies
Yushan LianZhimin HuangXinyi LiuZhicheng DengDan GaoXiaohui WangPublished in: Current HIV research (2024)
A drug screening system using Rev-A3R5-GFP reporter cells with pseudoviruses (pNL4-3) is highly efficient. This study provided potential hit compounds for new HIV drug research.
Keyphrases
- highly efficient
- antiretroviral therapy
- hiv positive
- hiv testing
- hiv infected
- human immunodeficiency virus
- hepatitis c virus
- hiv aids
- men who have sex with men
- induced apoptosis
- cell cycle arrest
- crispr cas
- adverse drug
- south africa
- oxidative stress
- signaling pathway
- drug induced
- cell death
- emergency department
- human health
- risk assessment
- case control
- climate change