Changes in the medial prefrontal cortex metabolites after 6 months of medication therapy for patients with bipolar disorder: A 1 H-MRS study.

Haijin LiJu GaoHuihui SongXuna YangCai LiYue ZhangJiahui WangYitong LiuDong Wang Hong Li

Published in: CNS neuroscience & therapeutics (2024)

This study suggests that NAA/Cr + PCr ratios and Gln/Cr + PCr ratios in the mPFC may be associated with manic and depressive episodes, implicating that Gln and NAA might be useful biomarkers for distinguishing mood phases in BD and elucidating its mechanisms.

Keyphrases

bipolar disorder
major depressive disorder
prefrontal cortex
ms ms
emergency department
physical activity
depressive symptoms
real time pcr
sleep quality